To celebrate its 78th anniversary, the Faculty of Pharmacy Universitas Gadjah Mada, Yogyakarta, Indonesia in collaboration with the Asian Pharmacometrics Network (APN), will organize the 6th APN Annual Workshop and Symposium 2024.
The theme of the event is “Pharmacometrics in the Optimization of Drug Development and Clinical Therapy”. The event will consist of a pre-symposium workshop and the main symposium.
Registration is free of charge for workshop, symposium and both events!
Registration is opened until 15 November 2024 at 23.59 Jakarta time (GMT +7).
A. APN 2024 Pre-symposium Workshop
“Handling Pharmacometrics Case Study in the Optimization of Drug Development and Clinical Therapy”
| Time (GMT +7, Jakarta time) | Agenda | Speaker |
| 08.00 – 08.15 | Opening speech by Dean Faculty of Pharmacy UGM | Prof. Dr. Satibi (Dean FF UGM) |
| 08.15 – 08.45 | Introduction of Case I and II | Prof. Dr. Surulivelrajan Mallayasamy |
| 08.45 – 09.00 | Break | |
| 09.00 – 09.30 | Software Tutorial | Prof. Akhmad Kharis Nugroho |
| 10.00 – 12.00 | Group Assignment and Discussion | Prof. Dr. Surulivelrajan Mallayasamy
Prof Kharis |
| 12.00 – 13.00 | Break | |
| 13.00 – 14.00 | Presentation of Case I | Prof. Dr. Surulivelrajan Mallayasamy |
| 14.00 – 15.00 | Presentation of Case II | Prof. Akhmad Kharis Nugroho |
| 15.00 – 15.30 | Concluding remark of APN Workshop | Prof. Dr. Surulivelrajan Mallayasamy
Prof. Akhmad Kharis Nugroho |
B. The 6th APN Annual Workshop and Symposium 2024
Day 1: Tuesday, 19 November 2024
| Time (GMT +7, Jakarta time) | Agenda | Speaker |
| 08.00 – 08.15 | Opening speech by Dean Faculty of Pharmacy UGM | Prof. Dr. Satibi (Dean FF UGM) |
| 08.15 – 08.30 | Opening remark of APN 2024 Symposium | Prof. Kyungsoo Park |
| 08.30 – 09.45 | Keynote Lecture Day 1:
Update in ICH-15 on the strategic role of Pharmacometrics in Accelerating MIDD |
Dr. Jenny Chien
Panelists: a. Dr. Daisuke Iwata b. Dr. Norisuke Kawai c. Kennya Nakai |
| 09.45 – 10.00 | Break | |
| 10.00 – 12.00 | APN lectures session 1 | 1. Dr. Rujia Xie
2. Prof. Chen Zhao 3. Prof. Eun Kyoung (“Christina”) Chung, PharmD, PhD 4. So Jin Lee, Pharm.D., Ph.D. |
| 12.00 – 13.00 | Break | |
| 13.00 – 14.00 | Student contribution Day 1 | Student 1
Student 2 Student 3 Student 4 |
| 14.00 – 15.30 | APN lectures session 2 | 5. Dr. Hua Wei
6. Naoi Sotaro, PhD 7. Dr. Yue Fang |
| 15.30 – 15.45 | Closing day 1 | MC |
Day 2: Wednesday, 20 November 2024
| Time (GMT +7, Jakarta time) | Agenda | Speaker |
| 08.30 – 08.45 | Opening of Day 2 Symposium | MC |
| 08.45 – 10.45 | APN Lectures Session 3 | 8. Prof. Dr. Surulivelrajan Mallayasamy, (India)
9.Prof Akhmad Kharis Nugroho 10.Dr Sabariah Noor Harun 11. Akihiro Yamada, Ph.D. |
| 10.45 – 11.00 | Break | MC |
| 11.00 – 12.30 | APN Lectures Session 4 | 12. Prof. Muhammad Fawad Rasool (Pakistan)
13. Prof. Hwi-yeol Yun, PhD 14. Dr Siti Maisharah S Ghadzi (Malaysia) |
| 12.30 – 13.30 | Lunch Break | |
| 13.30 – 14.30 | Student contribution Day 2 | Student 5
Student 6 Student 7 Student 8 |
| 14.30 – 15.00 | Concluding remarks of APN Symposium and workshop | Prof. Kyung Soo Park |
SPEAKERS LIST
A. KEYNOTE LECTURES
| Presenter Name | Presentation Title | Institution | Country | |
| Keynote Speaker 1 | Dr. Jenny Chien
Panelists: a. Dr. Daisuke Iwata b. Dr. Norisuke Kawai c. Kennya Nakai |
Update of ICH-15 on the strategic role of Pharmacometrics in Accelerating MIDD | Ely Lilly USA | USA |
B. APN INVITED LECTURES
| Presenter Name | Presentation Title | Institution | Country | |
| Invited Speaker 1 | Dr. Rujia Xie | MIDD to Support New Drug Applications | Pharmetheus | Singapore |
| Invited Speaker 2 | Prof. Chen Zhao | Progress and applications of QSP modeling in the development of new therapeutic modalities | Nanjing Medical University | China |
| Invited Speaker 3 | Prof. Eun Kyoung (“Christina”) Chung, PharmD, PhD | Regulatory Aspects of Integrating Pharmacometrics and Real-World Data | Associate Professor of Clinical Pharmacy
Kyung Hee University |
Korea |
| Invited Speaker 4 | So Jin Lee, Pharm.D., Ph.D. | Pediatric Pharmacokinetics and Dose Predictions using Pharmacometrics: A real-world example | Lead of Pharmacometrics
AIMS |
Korea |
| Invited Speaker 5 | Dr. Hua Wei | Integrated Modeling Approaches in the Development of Elranatamab: PMx and QSP Analyses | Pfizer (China) Research & Development Center | China |
| Invited Speaker 6 | Naoi Sotaro, PhD | Mechanistic Modeling in Engineered Antibody Drug Discovery and Development | Research Division, Chugai Pharmabody Research, Singapore | Japan |
| Invited Speaker 7 | Dr. Yue Fang | QSP application in Inflammatory Bowel Disease (IBD) | Pfizer (China) Research & Development Center | China |
| Invited Speaker 8 | Prof. Dr. Surulivelrajan Mallayasamy, | Predictive performance of Population pharmacokinetic models of Imatinib in Chronic Myeloid Leukemia patients | Centre for Pharmacometrics, Manipal College of Pharmaceutical Sciences, Manipal Academy of Higher Education, Manipal, India | India |
| Invited Speaker 9 | Prof Akhmad Kharis Nugroho | Therapeutics Drug Monitoring of Meropenem | Faculty of Pharmacy Unviersitas Gadjah Mada | Indonesia |
| Invited Speaker 10 | Dr Sabariah Noor Harun | Pharmacokinetic Modeling of Insulin in Acute Ischemic Stroke-Induced Hyperglycemia in Patients with Concomitant Diabetes | (Universiti Sains Malaysia) | Malaysia |
| Invited Speaker 11 | Akihiro Yamada, Ph.D. | Case Examples for Quantitative Systems Pharmacology Modeling and Simulation Application for Drug Development | New Technology, Early Development, Astellas Pharma Inc. | Japan |
| Invited Speaker 12 | Prof. Muhammad Fawad Rasool | Modeling Drug Exposure in Chronic Diseases: Insights from Physiologically Based Pharmacokinetic Approaches | Bahauddin Zakariya University, Multan | Pakistan |
| Invited Speaker 13 | Prof. Hwi-yeol Yun, PhD | Data driven compartmental modeling by mixed effect state space model | Professor of Pharmacy
Chungnam National University |
Korea |
| Invited Speaker 14 | Dr Siti Maisharah S Ghadzi | Pharmacometrics modelling in clinical practice: Insights from clozapine therapy | (Universiti Sains Malaysia) | Malaysia |
Student session
- Foong Keng Wah (Universiti Malaya), topic: Population Pharmacokinetics of IV Lidocaine and its Metabolites in Adult Surgical Patients
- Mohd. Rahimi bin Muda (Universiti Sains Malaysia and Universiti Teknologi Mara, Malaysia), topic: The impact of ABCB1 and SLCO1B1 genetic polymorphism on the pharmacokinetics of rifampicin among pulmonary tuberculosis patients: A population pharmacokinetics analysis
- Sohail Aziz (Universiti Sains Malaysia) Topic: Pharmacometrics Disease Progression Modelling of HbA1C among T2DM patients
- Yu-Ting Huang (School of Pharmacy, College of Medicine, National Taiwan University, Taipei, Taiwan) Topic: Application of Physiologically-Based Pharmacokinetic Modeling to Digoxin Therapeutic Drug Monitoring in Renal Impairment
- NGUYEN Thi Cuc (National Center of Drug Information and Adverse Drug Reaction Monitoring, Hanoi University of Pharmacy) Topic: Towards optimization dosing amikacin in the treatment of Klebsiella pneumoniae infections in critically ill patients: Insights from pharmacokinetics and pharmacodynamics analyses
- Jared Loo Tun Fang (Universiti Sains Malaysia and Sunway Medical Centre, Malaysia), Topic: Population Pharmacokinetics Modelling of Amikacin in Neutropenic Patients with Haematological Malignancy across Different Renal Function Equations
- Jun Seok Cha (Department of Pharmacology, Yonsei University College of Medicine) Topic: “Quantitative Systems Pharmacology of Beclin-1’s Dual Role in Ischemic Stroke”